DISEASE MOUSE MODELS
Disease Models
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Strain ID | Strain Name | Application |
T055223 | B6-Tg(hSOD1 G93A,hSOD1) | Genetic humanization, ALS disease |
T058996 | FAD4T-hTREM2 | Genetic humanization, Alzheimer's disease |
T054322 | B6-hSNCA E46K A53T | Genetic humanization, Parkinson's disease |
T056757 | B6-hCD36 | Genetic humanization, neuroinflammation |
T056002 | B6-Dmd Del45 | Duchenne muscular dystrophy, 45 exon deletion |
T055631 | B6-hDLL4 | Genetic humanization, oncology |
T056429 | B6-hCD34 | Genetic humanization, oncology |
T058753 | B6-hCEACAM5-Tg | Genetic humanization, oncology |
T053316 | B6-hIL18R1/hIL18RAP | Genetic humanization, oncology |
T037007 | B6-hCD47/hSIRPA | Genetic humanization, oncology |
T056010 | BALB/c-hCD44 | Genetic humanization, oncology |
T054198 | BALB/c-hGPC3 | Genetic humanization, oncology |
T054490 | BALB/c-hSEMA4D | Genetic humanization, oncology |
T054543 | BALB/c-hHSA | Genetic humanization, oncology |
T056432 | BALB/c-hTROP2 | Genetic humanization, oncology |
T056011 | BALB/c-hCD44v6 | Genetic humanization, oncology |
T055714 | BALB/c-hCS1 | Genetic humanization, oncology |
T056083 | BALB/c-hLRRC15 | Genetic humanization, oncology |
T056430 | BALB/c-hNECTIN-4 | Genetic humanization, oncology |
T058266 | BALB/c-hTIGIT/hPVRIG | Genetic humanization, oncology |
T054842 | BALB/c-hPD1/hPDL1/hTIGIT/hCD9 | Genetic humanization, oncology |
T058749 | BALB/c-hPD1/hPDL1/hCD73/hCD39 | Genetic humanization, oncology |
T009819 | BALB/c-hHER2 | Genetic humanization, oncology |
T009813 | NCG-hHER2 | Genetic humanization, oncology |
T054081 | NOD-Scid-hNKp30 | Genetic humanization, oncology |
T056195 | B6-hIGHA1 | Genetic humanization, autoimmune disease |
T054583 | BALB/c-hIL1RL1 | Genetic humanization, autoimmune disease |
T054645 | BALB/c-hKLRB1 | Genetic humanization, autoimmune disease |
T003277 | BALB/c-hIL17A | Genetic humanization, autoimmune disease |
T053555 | BALB/c-hIL1β | Genetic humanization, autoimmune disease |
T054186 | BALB/c-hTLR8 | Genetic humanization, autoimmune disease |
T055268 | BALB/c-hFcgRs/hCD47/hSIRPA | Genetic humanization, Fc end modification for antibody drugs, ADCC effect |
T058940 | BALB/c-hCD3EDG/hCD22 | Genetic humanization, CD3 bispecific antibody related |
T057420 | BALB/c-hCD73/hCD3EDG | Genetic humanization, CD3 bispecific antibody related |
T058817 | BALB/c-hGPRC5D/hCD3EDG | Genetic humanization, CD3 bispecific antibody related |
T059045 | BALB/c-hCD3EDG/hBCMA | Genetic humanization, CD3 bispecific antibody related |
T058351 | B6-Rosa26-hAGT | Genetic humanization, hypertension |
T058352 | B6-H11-hREN | Genetic humanization, hypertension |
T054639 | B6-hCD200R1 | Genetic humanization, atherosclerosis research |
T058217 | B6-hAPOB-Tg | Genetic humanization, hypercholesteremia and atherogenesis |
T058211 | B6-hAPOE-DGAT2-LE1 | Genetic humanization, NASH |
T051403 | B6-Myh6-R404Q | Hypertrophic cardiomyopathy |
T027708 | B6-Mybpc3-KO | hypertrophic cardiomyopathy or dilated cardiomyopathy |
T007085 | B6-Kras-G12D/wt; Lyz2-iCre | Spontaneous lung cancer |
T053603 | kras-G12C | Kras-related spontaneous tumors |
T057165 | KPS | Spontaneous lung cancer |
T057162 | KS | Spontaneous lung cancer |
