• 第2世代NCGモデル

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      Strain IDStrain NameApplicationStrain Type
      T037620huHSC-NCGReconstitute human immune cells (mainly T/B/NK) 

      Knockout (KO), CRISPR/Cas9, Immune recontitution

      T004886NCG-hIL15Promote human NK cells developmentKnockin (KI), CRISPR/Cas9
      T038070huHSC-NCG-hIL15Promote human NK cells development 

      Knockin (KI), CRISPR/Cas9, Immune recontitution

      T003802NCG-X

      Get rid of irradiation and promote erythroid cells development

      		Point mutation (PM), CRISPR/Cas9
      T017543NCG-hIL2Promote T cells developmentKnockin (KI), CRISPR/Cas9
      T036669NCG-MPromote lymphoid and myeloid cells developmentKnockin (KI), Knockout (KO), CRISPR/Cas9
      T003278NCG-HLA-A2.1Promote human cellular immune responsesKnockin (KI), CRISPR/Cas9
      T004670NCG-B2m-KOReduced xGVHDKnockout (KO), CRISPR/Cas9
      T050886NCG-MHC-dKOReduced xGVHDKnockout (KO), CRISPR/Cas9
      T003257NCG-HairlessHairlessKnockin (KI), CRISPR/Cas9
      T003575NCG-CAG-tdTomatoTransplanted visualizationKnockin (KI), CRISPR/Cas9